The name Botox has become shorthand for neurotoxin injectables that reduce the appearance of wrinkles and tighten the skin around your brow and eyes. Until now, all neurotoxin injectables have been similar to Botox in results and longevity. However, with Daxi (short for DaxibotulinumtoxinA), the world finally receives a long-acting Botox that maintains its result with as little as two treatments per year.
Revance Aesthetics released DaxibotulinumtoxinA for Injection, aka Daxi, which may be the world’s first long-lasting botulinum injectable. Daxi is currently an “investigational neuromodulator product,” which means it hasn’t yet been approved by the FDA. It’s likely to receive FDA approval in 2020. Once approved, we can treat our patients with Daxi, which may achieve frown line corrections with only two treatments per year.
As of now, there are four primary neuromodulator products for cosmetic treatments — Xeomin, Jeuveau, Dysport, and Botox. While the specific formulations may vary, all of them are based on the active ingredient Botulinum Toxin Type A, which is why they act similarly. When injected into the upper face, they prevent communication between the targeted muscles and nerves, reducing movement and smoothing out the skin in the region. In most cases, the effects of Botulinum Toxin Type A last for up to four months before wearing off.
The investigational neuromodulator product DaxibotulinumtoxinA for Injection has the same primary ingredient — Botulinum Toxin Type A. However, Daxi is made with a proprietary peptide formulation and a highly-purified botulinum toxin without animal-based components. This formulation allows Daxi to work as a long-acting botox. According to clinical studies, the effects of Daxi last around 24 weeks, which means you can maintain the results with only two treatments per year.
The primary benefit of Daxi is that it has greater longevity than traditional Botox and other similar neuromodulator products. According to clinical studies, it takes around 24 weeks for Daxi to start wearing off, and it takes around 28 weeks for your face to return to its original condition. Patients opting for Daxi neuromodulators will be able to retain the effects of their treatment with only two injections per year.
Like Botox, Daxi will be used to treat the wrinkles and frown lines on the upper half of the face. As of now, Daxi is being studied for glabellar (frown) lines, forehead lines, and crow’s feet. The FDA has already approved Daxi for the treatment of frown lines. Revance expects that Daxi will be approved for forehead lines and crow’s feet by the fourth quarter of 2020.
With over 25 years of experience, Dr. Grover is one of the most experienced and reputable plastic surgeons in the industry. Before the procedure, Dr. Grover will talk to you about your expectations and use that insight to curate the ideal treatment plan for your specific needs. Dr. Grover also actively educates his patients to ensure they know what to expect.
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